Dr. Wei Li's Laboratory
Institute of Genetics and Developmental Biology
Chinese Academy of Sciences, Beijing, China

[2016-2020] (BCH, CMU)

Research Papers (*corresponding author)

    (2016)
  1. Zhang W, Ren H, Xu C, Zhu C, Wu H, Liu D, Wang J, Liu L, Li W, Ma Q, Du L, Zheng M, Zhang C, Liu J, Chen Q. Hypoxic mitophagy regulates mitochondrial quality and platelet activation and determines severity of I/R heart injury. Elife, 2016; 5: e21407. [Abstract]
  2. Ma J, Zhang Z, Yang L, Kriston-Vizi J, Cutler DF*, Li W*. BLOC-2 subunit HPS6 deficiency affects the tubulation and secretion of von Willebrand factor from mouse endothelial cells. J Genet Genomics, 2016; 43(12): 686-693.[Abstract]
  3. Zhou W#, He Q# (# co-first authors), Zhang C, He X, Liu F*, Li W*. BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development. Elife, 2016; 5: e18108. [Abstract]
  4. Wei AH*,#, Yuan YF#, Bai DY# (# co-first authors), Ma J, Hao ZH, Zhang YZ, Yu JY, Zhou ZY, Yang L, Yang XM, Li L, Li W*. NGS-based 100-gene panel of hypopigmentation identifies mutations in Chinese Hermasky-Pudlak syndrome patients. Pigment Cell Melanoma Res, 2016; 29(6): 702-706. [Abstract]
  5. Hao ZH, Li W*. Muted protein is involved in the targeting of CD63 to large dense core vesicles of chromaffin cells. Heraditas (Beijing), 2016; 38(8): 718-724. [Chinese] [Abstract]
  6. Wei ZB#, Yuan YF# (# co-first authors), Jaouen F, Ma MS, Hao CJ, Zhang Z, Chen Q, Yuan ZQ, Yu L, Beurrier C, Li W*. SLC35D3 increases autophagic activity in mid-brain dopaminergic neurons by enhancing the BECN1-ATG14-PIK3C3 complex formation. Autophagy, 2016; 12(7): 1168-1179. [Abstract]
  7. Klionsky DJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 2016; 12(1): 1-222. [Abstract]

Book Chapters

  1. Li W, Ya D (Editors-in-chief). Genetics in Cartoon. Beijing: People's Health Publisher. 2016. [Chinese]

International Meeting Abstracts

  1. Wei A, Yuan Y, Bai D, Ma J, Zhou Z, Hao Z, Yu J, Zhang Y, Yang L, Yang X, Li L, Li W. Novel mutations in HPS1, 3, 5, 6 in Chinese Hermansky-Pudlak syndrome patients identified by NGS-based panel of hypopigmentation (#2541). 2016 Annual Meeting of American Society of Human Genetics. Vancouver, Canada. [poster]
  2. Hao Z, Li W, Liu X. Mutations of CFHR genes in Chinese atypical hemolytic uremic syndrome (aHUS) with CFH autoantibody positive (#2324). 2016 Annual Meeting of American Society of Human Genetics. Vancouver, Canada. [poster]

[2011-2015] (IGDB, CAS)

Research Papers (*corresponding author)

    (2015)
  1. Zhen YL, Li W*. Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A (D251E) mutation. Autophagy, 2015; 11(9): 1608-1622. [Abstract]
  2. Wei AH*, Zang DJ, Zhang Z, Yang XM, Li W*. Prenatal genotyping of four common oculocutaneous albinism genes in 51 Chinese families. J Genet Genomics, 2015; 42(6): 279-286. [Abstract]
  3. Hao Z, Wei L, Feng Y, Chen X, Du W, Ma J, Zhou Z, Chen L, Li W*. Impaired maturation of large dense core vesicles in muted-deficient adrenal chromaffin cells. J Cell Sci, 2015; 128(7): 1365-1374. [Abstract]
  4. Yuan Y, Wang H, Wei Z, Li W*. Impaired autophagy in hilar mossy cells of the dentate gyrus and its implication in schizophrenia. J Genet Genomics, 2015; 42(1): 1-8. [Abstract] (Cover Story)


  5. (2014)
  6. Wang H, Yuan Y, Zhang Z, Yan H, Feng Y, Li W*. Dysbindin-1C is required for the survival of hilar mossy cells and the maturation of adult newborn neurons in dentate gyrus. J Biol Chem, 2014; 289(42): 29060-29072. [Abstract] (Papers of the Week in JBC)
  7. Zhang A#, He X# (# co-first authors), Zhang L, Yang L, Woodman P, Li W*. Biogenesis of lysosome-related organelles complex-1 subunit 1 (BLOS1) interats with sorting nexin 2 and the endosomal sorting complex required for transport-I (ESCRT-I) component TSG101 to mediate the sorting of epidermal growth factor receptor into endosomal compartments. J Biol Chem, 2014; 289(42): 29180-29194. [Abstract]
  8. Li K, Yang L, Zhang C, Niu Y, Li W, Liu JJ. HPS6 interacts with dynactin p150Glued to mediate retrograde trafficking and maturation of lysosomes. J Cell Sci, 2014; 127(21): 4574-4588. [Abstract]
  9. Lin YY#, Wei AH# (# co-first authors), He X, Zhou ZY, Lian S, Zhu W. A comprehensive study of oculocutaneous albinism type 1 reveals three previously unidentified alleles on the TYR gene. Eur J Dermatol, 2014; 24(2): 168-173. [Abstract]
  10. Zhang Z#, Hao CJ# (# co-first authors), Li CG, Zang DJ, Zhao J, Li XN, Wei AH, Wei ZB, Yang L, He X, Zhen XC, Gao X, Speakman JR, Li W*. Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons. PLoS Genet, 2014; 10(2): e1004124. [Abstract] [Featured Article in PLoS G] [Media Coverage List] [CCTV News] [BBC News]
  11. Montoliu L, Gronskov K, Wei A, Martinez-Garcia M, Fernandez A, Arveiler B, Morice-Picard F, Riazuddin S, Suzuki T, Ahmed Z, Rosenberg T, Li W. Increasing the complexity: new genes and new types of albinism. Pigment Cell Melanoma Res, 2014; 27(1): 11-18.[Abstract]


  12. (2013)
  13. Wei AH*,#, Zang DJ#, Zhang Z#, Liu XZ# (# co-first authors), He X, Yang L, Wang Y, Zhou ZY, Zhang MR, Dai LL, Yang XM, Li W*. Exome sequencing identifies SLC24A5 as a candidate gene for non-syndromic albinism. J Invest Dermatol, 2013; 133(7): 1834-1840. [Abstract]
  14. Wei AH*, Li W*. Hermansky-Pudlak syndrome: Pigmentary and non-pigmentary defects and their pathogenesis. Pigment Cell Melanoma Res, 2013; 26(2): 176-192. [Abstract] (Featured on MDLinx.com)
  15. Wei AH, Yang XM, Lian S, Li W. Genetic analyses of Chinese patients with digenic oculocutaneous albinism. Chin Med J (Engl), 2013; 126(2):226-230. [Abstract] (Featured on MDLinx.com)
  16. Wei AH, He X, Li W*. Hypopigmentation in Hermansky-Pudlak syndrome (Invited Review). J Dermatol, 2013; 40(5): 319-324. [Abstract] (Featured on MDLinx.com).


  17. (2012)
  18. Meng R, Wang Y, Yao Y, Zhang Z, Harper DC, Heijnen HFG, Sitaram A, Li W, Raposo G, Weiss MJ, Poncz M, Marks M. SLC35D3 delivery from megakaryocyte early endosomes is required for platelet dense granule biogenesis and differentially defective in Hermansky-Pudlak syndrome models. Blood, 2012; 120(2): 404-414. [Abstract]
  19. Yang Q, He X*, Yang L, Zhou ZY, Cullinane AR, Wei AH, Zhang Z, Hao ZH, Zhang AL, He M, Feng YQ, Gao X, Gahl WA, Huizing M, Li W*. The BLOS1 interacting protein KXD1 is involved in the biogenesis of lysosome-related organelles. Traffic, 2012; 13(8): 1160-1169.[Abstract]
  20. Li HT, He X, Zhou ZY, Zhao SH, Zhang WX, Liu G, Zhao ZS, Jia B. Expression levels of Slc7a11 in the skin of Kazakh sheep with different coat colors. Heraditas (Beijing), 2012; 34(10): 1314-1319. [Chinese] [Abstract]
  21. Li XJ, Li W. Beyond mice: Genetically modifying larger animals to model human diseases (Editorial). J Genet Genomics, 2012; 39(6): 237-238.[Abstract]
  22. He X#, Li HT# (# co-first authors), Zhou ZY, Zhao ZS, Li W*. Production of brown/yellow coat color patches in the SLC7A11 transgenic sheep via testicular injection of transgene. J Genet Genomics, 2012; 39(6): 281-285. [Abstract]
  23. Li Y, Tan Z, Li Z, Sun Z, Duan S, Li W*. Impaired long-term potentiation and long-term memory deficits in xCT-deficient sut mice. Biosci Rep, 2012; 32(3): 315-321.[Abstract]
  24. Wang L#, He F#, Bu J#, Zhen Y# (# co-first authors), Liu X, Du W, Dong J, Cooney JD, Dubey SK, Shi Y, Gong B, Li J, McBride PF, Jia Y, Lu F, Soltis KA, Lin Y, Namburi P, Liang C, Sundaresan P, Paw BH, Li W, Li DY, Phillips JD, Yang Z. ABCB6 mutations cause ocular coloboma. Am J Hum Genet, 2012; 90(1): 40-48. Erratum: AJHG, 2012; 91(2): 397. [Abstract]
  25. Chen G, Zhang Z, Wei Z, Cheng Q, Li X, Li W, Duan S, Gu X. Lysosomal exocytosis in Schwann cells contributes to axon remyelination. Glia, 2012; 60(2): 295-305. [Abstract]


  26. (2011)
  27. Lin YY, Wei AH, Zhou ZY, Zhu W, He X, Lian S. A novel missense mutation of the TYR gene in a pedigree with oculocutaneous albinism type 1 from China. Chin Med J (Engl), 2011; 124(20): 3358-3361.[Abstract]
  28. Cheng J, Zhu Y, He S, Lu Y, Chen J, Han B, Petrillo M, Wrzeszczynski KO, Yang S, Dai P, Zhai S, Han D, Zhang MQ, Li W, Liu X, Li H, Chen ZY, Yuan H. Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64. Am J Hum Genet, 2011; 89(1): 56-66.[Abstract]
  29. Wei A, Yang X, Lian S, Li W*. Implementation of an optimized strategy for genetic testing of the Chinese patients with oculocutaneous albinism. J Dermatol Sci, 2011; 62(2): 124-127.[Abstract]

Book Chapters

  1. Du CS (Editor-in-chief), Li W#, Huang SZ#, Hua XY# (# associate editors). Medical Genetics (3rd edition). Beijing: People's Health Publisher. 2014. [Chinese]

International Meeting Abstracts

  1. Li W. SLC24A5 Mutation Causes OCA6. The 22nd International Pigment Cell Conference. Singapore, 2014. [invited]
  2. Zhang AL, He X, Woodman P, Li W. BLOS1 Interacts with SNX2 and TSG101 to Mediate Sequential Sorting of EGFR into Endosomal Compartments. Zing Conferences on Lysosome-Related Organelles. Nerja, Spain, 2014. [oral]
  3. Ma J, Yang L, Zhang Z, Dan Cutler, Li W. BLOC Deficiency Affects the Maturation and Exocytosis of Weibel-Palade Bodies in Vascular Endothelial Cells. Zing Conferences on Lysosome-Related Organelles. Nerja, Spain, 2014. [oral]
  4. Wei AH, Zang DJ, Zhang Z, Zhou ZY, Sviderskaya EV, Li W. Aberrant Localization and Trafficking of Melanosaml Proteins in Chinese OCA Patients. Zing Conferences on Lysosome-Related Organelles. Nerja, Spain, 2014. [oral]
  5. Hao ZH, Li W. The MUTED Protein is Involved in the Biogenesis of Large Dense Core Vesicles in Adrenal Chromaffin Cells. Zing Conferences on Lysosome-Related Organelles. Nerja, Spain, 2014. [poster]
  6. Li W. BLOC-1 Modulates EGF Signal Transduction through Endo-Lysosomal Trafficking. The 16th Asia-Pacific International Molecular Biology Network (A-IMBN) Annual Conference 2013, Singapore, 2013. [invited]
  7. Li W. Aging Related Defects in Lysosomal Trafficking Disorders. The 4th Sino-Australia Biomedicine Conference. Hangzhou, China, 2013. [invited]
  8. Li W The endosomal protein SLC35D3 regulates the membrane trafficking of D1 dopamine receptor. The 3rd International Symposium on Membrane Biology. Zhuhai, China, 2012. [invited]
  9. Li W. Altered membrane trafficking of striatonigral D1 receptor results in metabolic syndrome. The 17th International Biophysics Congress. Beijing, China, 2011. [invited]
  10. Li W. Blos4 is a novel subunit of the biogenesis of lysosome-related organelles complex-1 (BLOC-1). Gordon Research Conference: Molecular Membrane Biology. Andover, NH, USA, July, 2011 [poster]
  11. Wei A, Wang Y, Li W. An optimized strategy for genetic testing of the Chinese patients with oculocutaneous albinism. Pigment Cell Melanoma Res, 24(4): 812, 2011 [oral]
  12. Li W. Mouse models of albinism: insights into defects in development and trafficking. CAS International Symposium on Animal Models of Diseases. Beijing, China, 2011 [invited]

[2005-2010] (IGDB, CAS)

Research Papers (*corresponding author)

    (2010)
  1. Cui YY, Li XG, Chen QG, He X, Yang Q, Zhang AL, Yu X, Chen H, Liu NY, Xie Q, Yang WC, Zuo JR, Palme K*, Li W*. BLOS1, a putative BLOC-1 subunit, interacts with SNX1 and modulates root growth in Arabidopsis. J Cell Sci, 2010; 123(21): 3727-3733. [Abstract] [JCS Recommendation]
  2. Hao ZH, Li W*. Cellular functions of the lysosomal trafficking. Chinese Bull Life Sci , 2010; 23(11): 1138-1146. [Chinese]
  3. Liu XL, Zhang FL, Zhou ZY, Zhao HL, Shen GM, Baohan WY, Duan ZY, Li W*, Zhang JW*. Analysis of two sequence variants in peroxisome proliferator activated receptor gamma gene in Tibetan population at high altitudes and Han population at low altitudes in China. Med Sci Monit, 2010; 16(10): CR458-463. [Abstract]
  4. Zeng Y, Li Y, Chen RS, He X, Yang L*, Li W*. Overexpression of xCT induces upregulation of 14-3-3beta in Kaposi's sarcoma. Biosci Rep, 2010; 30(4): 277-283. [Abstract]
  5. Guo XL, Ruan HB, Li Y, Gao X, Li W*. Identification of a novel nonsense mutation on the Pax3 gene in ENU-derived white belly spotting mice and its genetic interaction with c-Kit. Pigment Cell Melanoma Res, 2010; 23(2): 252-262. [Abstract]
  6. Wei AH#, Wang Yu#, Long Y#, Wang Yi# (# co-first authors), Guo XL, Zhou ZY, Zhu W, Liu JT, Bian XM, Lian S*, Li W*. A comprehensive analysis reveals mutational spectra and common alleles in Chinese patients with oculocutaneous albinism. J Invest Dermatol, 2010; 130(3): 716-724. [Abstract] (Featured on MDLinx.com)
  7. Liu XL, Zhang FL, Zhou ZY, Zhao HL, Shen GM, Baohan WY, Duan ZY, Li W*, Zhang JW*. Analysis of two sequence variants in peroxisome proliferator activated receptor gamma gene in Tajik population at high altitudes and Han population at low altitudes in China. Mol Biol Rep, 2010; 37(1): 179-184. [Abstract]


  8. (2009)
  9. Wei AH, Lian S, Wang LJ, Li W*. The first case report of a Chinese Hermansky-Pudlak syndrome patient with a novel mutation on HPS1 gene. J Dermatol Sci, 2009; 56(2):130-132. [doi:10.1016/j.jdermsci.2009.07.007]
  10. Feng YQ, Li W. Susceptibility genes of schizophrenia. J Med Mol Biol, 2009; 6(6): 555-558. [Chinese]
  11. Zhang Z, Li W*. Formation and function of Weibel-Palade bodies. Hereditas (Beijing), 2009; 31(9): 882-888. [Chinese] [Abstract]
  12. He M#, Wang Y# (# co-first authors), Li W*. PPI Finder: A mining tool for human protein-protein interactions. PLoS ONE, 2009; 4(2):e4554. [Abstract]
  13. Chen RS, Song YM, Zhou ZY, Tong T, Li Y, Fu M, Guo XL, Dong LJ, He X, Qiao HX, Zhan QM*, Li W*. Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway. Oncogene, 2009; 28(4): 599-609. [Abstract]
  14. Wang Y, Guo XL, Wei AH, Zhu W, Li W*, Lian S*. Identification of a novel mutation in a Chinese family with X-linked ocular albinism. Eur J Ophthalmol, 2009; 19(1): 124-128. [Abstract]
  15. Wang Y, Guo XL, Li W*, Lian S*. Four novel mutations of TYR gene in Chinese OCA1 patients. J Dermatol Sci, 2009; 53(1): 80-81. [doi:10.1016/j.jdermsci.2008.07.002]


  16. (2008)
  17. Feng YQ, Zhou ZY, He X, Wang H,Guo XL, Hao CJ, Guo Y, Zhen XC, Li W*. Dysbindin deficiency in sandy mice causes reduction of snapin and displays behaviors related to schizophrenia. Schizophr Res, 2008; 106(2-3): 218-228. [Abstract]
  18. Chen XW#, Feng YQ# (# co-first authors), Hao CJ, Guo XL, He X, Zhou ZY, Guo N, Huang HP, Xiong W, Zheng H, Zuo PL, Zhang X, Li W*, Zhou Z*. DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release. J Cell Biol, 2008; 18(5): 791-801. [Abstract] [highlighted news in JCB] [research highlights in Nature China]
  19. Qiao HX, Hao CJ, Li Y, He X, Chen RS, Cui J, Xu ZH*, Li W*. JNK activation mediates the apoptosis of xCT-deficient Cells. Biochem Biophys Res Commun, 2008; 370(4): 584-588. [Abstract]
  20. Reeve SP, Lin XD, Sahin HB, Jiang FF, Yao AY, Liu ZH, Li W, Giangrande A, Hassan BA, Zhang YQ. Mutational analysis establishes a critical role for the N terminus of Fragile X mental retardation protein FMRP. J Neurosci, 2008; 28(12): 3221-3226. [Abstract]


  21. (2007)
  22. Li W*, Feng YQ, Hao CJ, Guo XL, Cui YY, He M, He X. The BLOC interactomes form a network in endosomal transport. J Genet Genomics, 2007; 34(8): 669-682. [Abstract] [PDF]
  23. He M, Li W*. PediDraw: A web-based tool for drawing a pedigree in genetic counseling. BMC Med Genet, 2007; 8:31. [ Abstract]
  24. He M, Li W*. China genetic counseling network (CGCN): A website on genetic counseling and genetic education. Hereditas (Beijing), 2007; 29(3): 381-384. [Chinese] [Abstract]
  25. Chintala S, Tan J, Gautum R, Rusiniak M, Guo XL, Li W, Gahl WA, Huizing M, Spritz RA, Hutton S, Novak EK, Swank RT. The Slc35d3 gene, encoding an orphan nucleotide sugar transporter, regulates platelet dense granules. Blood. 2007; 109(4): 1533-1540. (with commentary) [Abstract]


  26. (2006)
  27. Li W*, He M, Zhou HL, Bourne JW, Liang P. Mutational data integration in gene-oriented files of Hermansky-Pudlak syndrome database. Hum Mutat, 2006, 27(5): 402-407. [Abstract]


  28. (2005)
  29. Chintala S, Li W, Lamoreux ML, Ito S, Wakamatsu K, Sviderskaya EV, Bennett DC, Park Y-M, Gahl WA, Huizing M, Spritz RA, Ben S, Novak EK, Tan J, Swank RT. Slc7a11 controls the production of pheomelanin pigment and the proliferation of cultured cells. Proc Natl Acad Sci USA, 2005, 102 (31): 10964-10969. [Abstract] [PDF]

Book Chapter

  1. Li W. Genetics of intracellular traffic jams: multi-organellar defects. In Deng HW, Shen H, Liu YJ, Hu H. eds. Current Topics in Human Genetics: Studies in Complex Diseases. World Scientific Publishing Co. Pte. Ltd. 2007; 929-943.

Patents or Copyrights

  1. Li W, Wang Y. A Mutation Conversion Tool (v. 1.0). (2009SRBJ7775)
  2. Li W, He M, Wang Y. PPI Finder: Protein-Protein Interaction Text Mining Software (v. 1.0). (2008SRBJ2159)
  3. Li W, Qiao HX, Li Y, Ke ZJ, Xu ZH. New Roles of the Gene Encoding xCT. (ZL 200610089373.6)
  4. Li W, He M. PediDraw: Online Pedigree Drawing Software (v. 1.0). (2006SRBJ2033)

International Meeting Abstracts

  1. Li Y, Li W. Impaired long-term plasticity in the mice lacking xCT, a subunit of cystine/glutamate transporter. The Second International Symposium on Membrane Biology. Ningbo, China. p.71, 2010 [oral]
  2. Li W, Wei A, Wang Y. Online genetic counseling for albinism in China. The 9th Asia Pacific Conference on Human Genetics. Hong Kong, China. p.p. 76-77, 2010 [invited]
  3. Li W. AtBLOS1, a putative BLOC-1 subunit, interacts with AtSNX1 and modulates auxin efflux transporters and root growth in Arabidopsis. Gordon Research Conference--Lysosomes & Endocytosis (#55). Andover, USA, 2010 [poster]
  4. Li W, Wei A, Wang Y, Long Y, Wang Y, Guo X, Zhou Z, Bian X, Lian S. The spectrum of mutational genes and alleles in Chinese OCA patients. The 59th Annual Meeting of The American Society of Human Genetics (#441). Honolulu, USA, 2009 [poster]
  5. Li Y, Chen RS, Qiao HX, Li W. Glutamate/cystine antiporter system xc- in regulating pigment biogenesis, cell proliferation and invasion, neuronal function. Amino Acids, 37(Suppl. 1): S20-S21, 2009 [oral]
  6. Li W. Novel interactions and functions of biogenesis of lysosome-related organelles complex-1 (BLOC-1). The First International Symposium on Membrane Biology. Guilin, China. p.p. 24-25, 2009 [invited]
  7. Li W, Wang Y, Guo XL, Lian S. Three novel mutations of TYR gene in Chinese OCA1 patients. Pigment Cell Melanoma Res, 21(2): 311-312, 2008 [poster]
  8. Li W, Guo XL, Gao X. A novel ENU-derived mouse model of Waardenburg syndrome and its genetic interaction. Pigment Cell Melanoma Res, 21(2): 309, 2008 [poster]
  9. Feng YQ, Chen XW, Hao CJ, Guo XL, Zhang X, Guo Y, Zhen XC, Zhou Z, Li W. Genes in regulating the biogenesis of lysosome-related organelles. Prog Biochem Biophys, 34 (Suppl. 1): 36, 2007 [invited]
  10. Qiao HX, Hao CJ, Li Y, Cui J, Xu ZH, Li W. JNK pathway activation modulates ER stress and oxidative stress during the apoptosis of xCT-deficient cells. Prog Biochem Biophys, 34 (Suppl. 1): 80, 2007 [poster]
  11. Feng Y, He M, Hao C, Guo X, Cui Y, He X, Li W. The BLOC-1 interactome in endosomal transport. The American Society for Cell Biology and European Cytoskeleton Forum (#58). Dijon, France. p.30, 2007 [poster]
  12. Li W. Systems biology techniques in dissecting intracellular vesicle trafficking pathways. International Conference on Bio-Nano-Informatics Fusion 2006. Beijing, China. p.p. 23-25, 2006 [invited]
  13. Li W. He M, Zhou HL, Bourne JW, Liang P. Data integration in gene-oriented files of Hermansky-Pudlak syndrome database. 11th International Congress of Human Genetics (#1498). Brisbane, Australia. p.263, 2006 [poster]
  14. Gautam R, Rusiniak ME, Chintala S, Tan J, Li W, Novak EK, Reddington M, Swank RT, McGarry MP. A new gene which regulates platelet dense granules. Blood, 106 (11): 615A, 2005 [poster]
  15. Li W. Cystine/Glutamate Transporter in Regulating Oxidative Stress. 3rd Beijing International Symposium on Neurodegenerative Diseases and Stroke. Beijing, China. p.252, 2005 [invited]
  16. Li W. Murine Models of Hermansky-Pudlak Syndrome in Dissecting Intracellular Vesicle Trafficking Pathways. World DNA and Genome Day. Dalian, China. p.p. 31-32, 2005 [invited]

[1999-2004] (RPCI, USA)

RESEARCH PAPERS

  1. Li W, Rusiniak M, Chintala S, Gautum R,Novak EK, Swank RT. Murine Hermansky-Pudlak syndrome:Genes which control lysosome-related organelles. BioEssays,2004, 26 (6): 616-628 (featured with cover story) [Abstract] [PDF]
  2. Gautum R, Chintala S, Li W, Zhang Q, Tan J,Di Pietro SM, Dell'Angelica EC, Novak EK, Swank RT.The Hermansky-Pudlak syndrome 3 (cocoa) protein is acomponent of the biogenesis of lysosome-related organelle complex 2 (BLOC-2). J Biol Chem, 2004, 279(13): 12935-12942 [Abstract] [PDF]
  3. Zhang L, Li S, Zhao C, Peng PJ, Huang PY, Li W. Correlation between plasma EBV DNA and tumor recurrence in nasopharyngeal carcinoma. Chinese Clin Oncol, 2004; 9(2):122-125. [Chinese]
  4. Rui DR, Yan ZH, Li W, He YS. Detection of alpha-thelassemia by multiplex PCR. Chinese J Clin Lab Sci, 2004; 22(3):186-187. [Chinese]
  5. Li W*, Zhang Q*, Oiso N* (*co-first authors), Novak EK, Gautum R, O'Brien EP, Tinsley CL, Blake DJ, Spritz RA, Copeland NG, Jenkins NA, Amato D, Boe BA, Starcevic M, Dell'Angelica EC, Elliott RW, Mishra VS, Kingsmore SF, Swank RT. Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1). Nat Genet, 2003, 35 (1): 84-89 [Abstract]
  6. Zhang Q*, Zhao B*, Li W*, Oiso N* (*co-first authors), Novak EK, Rusiniak ME, Gautam R, Chintala S, O'Brien EP, Zhang Y, Roe BA, Elliott RW, Eicher EM, Liang P, Kratz C, Legius E, Spritz RA, O'Sullivan TN, Copeland NG, Jenkins NA, Swank RT. Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6. Nat Genet, 2003; 33(2): 145-153 (Article) [Abstract]
  7. Gao H, Li W, Yan ZH, Jiang MH, Rui DR, He YS. Molecular characterization of a new mutation E122G of human ornithine transcarbamylase gene. Chinese J Med Genet, 2003; 20(1):19-22. [Chinese] [Abstract]
  8. Zhang Q, Zhen L, Li W, Novak EK, Collinson LM, Jang EK, Haslam R, Elliott RW, Swank RT. Cell specific abnormal prenylation of Rab proteins in platelets and melanocytes of the gunmetal mouse. Br J Hematol,2002; 117(2): 414-423 [Abstract]
  9. Zhang Q*, Li W* (*co-first authors), Novak EK, Karim A, Mishra VS, Kingsmore SF, Roe BA, Suzuki T, Swank RT. The gene for the muted (mu) mouse, a model for Hermansky-Pudlak syndrome, defines a novel protein which regulates vesicle trafficking. Hum Mol Genet 2002; 11(6): 697-706 [Abstract] [PDF]
  10. Suzuki T, Li W, Zhang Q, Karim A, Novak EK, Sviderskaya EV, Hill SP, Bennett DC, Levin AV, Nieuwenhuis HK, Fong CT, Castellan C, Miterski B, Swank RT, Spritz RA. Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene. Nat Genet, 2002; 30(3): 321-324 [Abstract]
  11. Suzuki T*, Li W* (*co-first authors),Zhang Q, Novak EK, Sviderskaya EV, Wilson A, Bennett DC, Roe BA, Swank RT, Spritz RA. The gene mutated in cocoa mice, carrying a defect of organelle biogenesis, is a homologue of the human Hermansky-Pudlak syndrome-3 gene. Genomics, 2001; 78(1/2): 30-37 [Abstract]
  12. Li W, Elliott RW, Novak EK, Swank RT. cDNA sequence and mapping of the mouse Copb gene encoding the beta subuint of COPI coatomer complex. Somat Cell Mol Genet, 1999; 25(3): 177-183 [Abstract]
  13. Swank RT, Novak EK, McGarry MP, Zhang Y, Li W, Zhang Q, Feng L. Abnormal vesicular trafficking in mouse models of Hermansky-Pudlak Syndrome (review). Pigment Cell Res, 2000; 13: 59-67 [Abstract]
  14. Li W, Detter JC, Weiss HJ, Cramer EM, Zhang Q, Novak EK, Kingsmore SF, Swank RT. 5'UTR structural organization, transcript expression and single nucleotide polymorphisms of human Rab Geranylgeranyl transferase alpha subunit (RABGGTA) gene. Mol Genet Metab, 2000; 71(4): 599-608 [Abstract]
  15. Detter JC, Zhang Q, Mules EH, Novak EK, Mishna VS, Li W, McMurtrie EB, Tchernev VT, Wallace MR, Seabra MC, Swank RT, Kingsmore SF. Rab geranylgeranyl transferase a mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis. Proc Natl Acad Sci U.S.A. 2000; 97(8): 4144-4149 [Abstract] [PDF]

BOOKS

  1. Li W, Hu ZH, Liang P (editors-in-chief). Introduction to Bioinformatics. Zhengzhou: Zhengzhou University Press. 2004, Chinese
  2. Li W, He YS (editors-in-chief). Genetic Counseling. Zhengzhou: Zhengzhou University Press. 2003, Chinese
  3. Li W, Li W, Huang YY, Pang W, (editors-in-chief). Prenatal Genetic Diagnosis. Guangzhou: Guangdong Science & Technology Press. 2002, Chinese

ABSTRACTS (selected from international meetings)

  1. Li W, Liang P, Swank RT. Gene-oriented file system: the development of a Hermansky-Pudlak syndrome database (#2410). Abstract of the 54th Annual Meeting of The American Society of Human Genetics, Toronto, Canada, 2004 [poster]
  2. Li W, Zhang Q, Oiso N, Novak EK, Gautum R, O'Brien EP, Tinsley CL, Blake DJ, Spritz RA, Copeland NG, Jenkins NA, Amato D, Boe BA, Starcevic M, Dell'Angelica EC, Elliott RW, Mishra VS, Kingsmore SF, Swank RT. Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutations of dysbindin, a new member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1). Am J Hum Genet, 73(5): 219 Suppl, 2003 [oral]
  3. Zhang Q, Li W, Novak EK, Chen H, He Y, Roe BC, Copeland NG, Jenkins NA, Swank RT. Identification of the mouse ruby-eye-2(ru2) gene, a candidate gene for human Hermansky-Pudlak Syndrome. Abstract of HUGO's 7th International Human Genome Meeting, Shanghai, China, 2002 [poster]
  4. Spritz R, Suzuki T, Novak E, Zhang Q, Li W, et al. Identification of the mouse cocoa (coa) gene, a candidate gene for human Hermansky-Pudlak syndrome (HPS). Am J Hum Genet, 69(4): 146 Suppl. 2001 [poster]
  5. Suzuki T, Novak E, Zhang Q, Li W, et al. The human homolog of mouse light ear (le) is a major gene for Hermansky-Pudlak sydrome (HPS). Am J Hum Genet, 69 (4): 212 Suppl. 2001 [oral]
  6. Zhang Q, Li W, Novak EK, Karim A, Mishra V, Kingsmore S, Roe BA, Swank RT. The gene for the muted (mu) mouse, a model for Hermansky-pudlak syndrome, defines a novel protein which regulates vesicle trafficking. Abstract of 15th International Mouse Genome Conference, Edinburgh, Scotland, 2001 [oral]
  7. Li W, Detter JC, Weiss HJ, et al. Structural organization, transcript expression and mutational analysis of the human Rab geranylgeranyl transferase alpha-subunit (RABGGTA) gene. Am J Hum Genet, 67(4): 2160 Suppl. 2000 [poster]
  8. Lin J, Liao S, Han J, Wang C, Zhou M, Wu C, Huang W, Kang C, Li W. Correlation between neonatal hepatitis B and maternal serum hepatitis B virus DNA copies (#2021). Pediatric Academic Society & American Academy of Pediatrics Joint Meeting Year 2000 Abstracts, Boston, USA, 2000 [poster]
  9. Li W, Mishna VS, Zhang Y, Zhang Q, Novak EK, Jenkins NA, Copeland NG, Kingsmore SF, Swank RT. High-resolution mapping and transcript identification at the sdy locus on mouse chromosome 13 (#F40). Abstract of the 13th International Mouse Genome Meeting, Philadelphia, USA, 1999 [poster]

[Before 1999]

Publications in Chinese